Down Syndrome between Genetic Hazard and Divine Decision

The Down syndrome (DS) represents the most frequent chromosomal disease determined by the presence of a supernumerary chromosome 21. The existence of the third chromosome 21 affects most of the tissues and organs, through the appearance of a suggestive craniofacial dysmorphia, various visceral malformations and psychomotor retard, the most common error being the maternal non-disjunction in the first meiotic division. Despite all the genetics progresses, the DS pathology has not been completely elucidated, the advanced maternal age (over 35) being at present the only determinant factor clearly responsible for the maternal meiotic non-disjunction. So far, the scientists do not know why sometimes the cells abnormally divide and produce additional genetic material (the third chromosome 21, in this case) which results in the DS appearance; who gives this verdict: the hazard, happening, or lawswhose laws? Did the life make its own laws and is subjected to them? Do the laws belong to those who found them or to the One who made them? Going beyond the science frontiers and listening to the Scripture text (“I the Lord your God am a jealous God visiting the iniquity of the fathers upon the children to the third and fourth generation at those who hate me but showing steadfast love to thousands of those who love me and keep my commandments”), we understand that the Author of Life and its laws is God, and not the hazard. He is the primary cause which configures the life in all its peculiarities, He decides our only configuration, without affecting the freedom of action of the man who chooses the sin or respects the laws of life and divinity.